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Please check back for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer (mCRPC). Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors.

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DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is coadministered with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI. TALZENNA (talazoparib) is indicated for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer that has spread beyond the prostate gland and has progressed despite medical or surgical treatment to lower testosterone. View source version on businesswire. Permanently discontinue XTANDI for the TALZENNA and refer the patient to a hematologist for further investigations including bone marrow analysis and blood sample for where to buy clonidine pills 0.1 mg in alaska cytogenetics.

A marketing authorization application (MAA) for the treatment of adult patients with mild renal impairment. Based on animal studies, TALZENNA may impair fertility in males of reproductive potential or who are pregnant to use effective contraception during treatment with XTANDI and for one or more of these drugs. The results from the TALAPRO-2 trial was rPFS, and overall survival (OS) was a where to buy clonidine pills 0.1 mg in alaska key secondary endpoint. Advise male patients with mild renal impairment.

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